What event occurs during anaphase of mitosis?

During anaphase of mitosis, the key event that occurs is the separation of sister chromatids. This is when the chromatids, which were previously joined at the centromere, are pulled apart toward opposite poles of the cell. The process is facilitated by the shortening of microtubules attached to the kinetochores, ensuring that each new daughter cell will receive an identical set of chromosomes.

The movement of the chromatids to opposite sides of the cell is crucial for the accurate distribution of genetic material, laying the groundwork for cell division that will ultimately result in two genetically identical daughter cells. This separation marks a significant transition in mitosis, leading towards the completion of the division process in subsequent phases.

In contrast, during other phases of mitosis such as metaphase, the chromatids align at the cell’s equator, while in telophase, the nuclear membranes begin to reform. Replication of chromosomes occurs in the S phase of interphase, prior to the initiation of mitosis. Understanding these distinct phases helps clarify the progression of mitosis and the importance of anaphase in ensuring genetic fidelity during cell division.